PATIENT EDUCATION
EFFECTS OF MEDICATIONS ON VOICE
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Diseases and disorders of the ears, nose, throat, head, and neck negatively impact the lives of millions around the world. Our health information, created by our member physicians, provides a basic overview of diagnoses and treatment for many of these conditions.
Ears
Conditions that impair ear function can be as minor as wax buildup or as serious as congenital deafness. This section contains valuable information about how to protect your hearing, how to recognize indications of hearing disorders, and what ENT-head and neck physicians can do to evaluate and treat these problems. Learn More »
Throat
Maladies of the throat can be a mere nuisance or a major ordeal. Tonsillitis, voice disorders, and even hoarseness all interfere with our ability to communicate. Many of these conditions can be improved or corrected with the care of an ENT physician or head and neck surgeon. Learn More »
Nose and Mouth
Congestion, allergic rhinitis, a deviated septum, and mouth sores are just a few of the varied health problems that occur in this region of the body. Information about ways you can relieve symptoms at home and when you should see a physician can be found in this section. Learn More »
Head and Neck Surgery
Many surgical advances are being made in this area. Procedures such as tonsillectomy and facial plastic surgery are becoming less invasive, and new procedures are being developed to treat serious problems such as cleft palate, sleep apnea, and deafness. Learn More »
Cancer
Early detection is critical to preventing fatal outcomes. Cancers of the head and neck such as laryngeal cancer can be particularly aggressive. Signs of cancer of the head and neck include changes in the skin, pain, prolonged hoarseness, and sudden loss of voice. If you suffer from any of these symptoms you should see an ENT or head and neck physician immediately. Learn More »
Pediatric
Children face many of the same health problems that adults do, however symptoms may show themselves differently and treatment methods that work well in adults may not be appropriate for children. This section identifies common pediatric ENT, head, and neck ailments and what you should ask your child’s doctor about diagnosis and treatment. Learn More »
Could Your Medication Be Affecting Your Voice?
Some medications including prescription, over-the-counter, and herbal supplements can affect the function of your voice. If your doctor prescribes a medication that adversely affects your voice, make sure the benefit of taking the medicine outweighs the problems with your voice.
Most medications affect the voice by drying out the protective mucosal layer covering the vocal cords. Vocal cords must be well-lubricated to operate properly; if the mucosa becomes dry, speech will be more difficult. This is why hydration is an important component of vocal health.
Medications can also affect the voice by thinning blood in the body, which makes bruising or hemorrhaging of the vocal cord more likely if trauma occurs, and by causing fluid retention (edema), which enlarges the vocal cords. Medications from the following groups can adversely affect the voice:
- Antidepressants
- Muscle relaxants
- Diuretics
- Antihypertensives (blood pressure medication)
- Antihistamines (allergy medications)
- Anticholinergics (asthma medications)
- High-dose Vitamin C (greater than five grams per day)
- Other medications and associated conditions that may affect the voice include:
- Angiotensin-converting-enzyme (ACE) inhibitors (blood pressure medication) may induce a cough or excessive throat clearing in as many as 10 percent of patients. Coughing or excessive throat clearing can contribute to vocal cord lesions.
- Oral contraceptives may cause fluid retention (edema) in the vocal cords because they contain estrogen.
- Estrogen replacement therapy post-menopause may have a variable effect.
- An inadequate level of thyroid replacement medication in patients with hypothyroidism.
- Anticoagulants (blood thinners) may increase chances of vocal cord hemorrhage or polyp formation in response to trauma.
- Herbal medications are not harmless and should be taken with caution. Many have unknown side effects that include voice disturbance.
NOTE: Contents of this fact sheet are based on information provided by The Center for Voice at Northwestern University.